Halogen atom transfer (XAT) is a versatile method for generating carbon radicals. Recent interest has focused on α-aminoalkyl radicals as potential XAT reagents, previously reported to exhibit reactivity comparable to tin radicals. Utilizing an …
Enamine-derived radicals are crucial intermediates in singly occupied molecular orbital (SOMO) catalysis. However, observing them directly is elusive and remains a long-standing challenge. Here, an advanced time-resolved electron paramagnetic …
Molecular photocatalysis has shown tremendous success in sustainable energy and chemical synthesis. However, visualizing the intricate mechanisms in photocatalysis is a significant and long-standing challenge. By employing our recently developed …
As an important elementary step in organometallic chemistry, the alkylation reaction of palladacycle complexes and alkyl halides has attracted much attention in recent years due to their presence as key step in palladium catalyzed C-H alkylation …
Diboron(4) compounds serve as useful reagents for borylation, diboration, and reduction in organic synthesis. A variety of pyridine derivatives have been found capable of activating diboron(4) compounds, and different reaction mechanisms have been …
The combination of small organic molecules and a base serves as a unique system for the activation carbon– halogen bonds in haloarenes by single electron transfer (SET). However, most of the molecules employed as promoters only allow for the …
Activation of the carbon– halogen bonds in aryl halides is a key step in transition-metal-free cross-coupling reactions. In this paper, a new and efficient radical initiation system for the activation of iodoarenes to produce aryl radicals was …
Radical chain reactions leading to C– C bond formation are widely used in organic synthesis, and initiation of the radical chain process usually requires thermolabile radical initiators. Recent studies on transition-metal-free cross-coupling …