Chen-Hui’s Work on Pd(II)/SOHP-Catalyzed C-H Arylation of Primary Aliphatic Amines Published in Org. Lett.

Congratulations to Chen-Hui Yuan for the publication of his work on Pd(II)/SOHP catalysis in Org. Lett. (doi:10.1021/acs.orglett.3c03186)!

This work is the third of our series works on Pd(II)/sulfoxide-2-hydorxypyridine ligand (SOHP) catalysis (for previous advances, please refer to Chem. Sci. 2020, 11, 742 and Angew. Chem. Int. Ed. 2023, e2023000854). Chen-Hui extended the scope of this catalytic system to native primary amine, whose methyl C-H bond at the γ-position could be smoothly activated and arylated.